Memcached is a distributed, high-speed caching system that stores simple key-value pairs in memory. It’s ideal for quick, transient data storage without persistence or complex features.

Redis is a distributed, open-source, in-memory data store used as a cache, database, and message broker. It supports advanced data structures and features like persistence, replication, and clustering.

Yes, you can configure IDistributedCache in .NET to use either Redis or Memcached as the backend cache provider. This allows you to use the distributed caching infrastructure of .NET while leveraging the power of Redis or Memcached to store the data.